Stephanie Seneff

Stephanie Seneff


Stephanie Seneff is a Senior Research Scientist at the MIT Computer Science and Artificial Intelligence Laboratory.  She received the B.S. degree in Biophysics in 1968, the M.S. and E.E. degrees in Electrical Engineering in 1980, and the Ph.D degree in Electrical Engineering and Computer Science in 1985, all from MIT.  For over three decades, her research interests have always been at the intersection of biology and computation – developing a computational model for the human auditory system, understanding human language so as to develop algorithms and systems for human computer interactions, as well as applying natural language processing (NLP) techniques to gene predictions.   She has published over 170 refereed articles on these subjects, and has been invited to give keynote speeches at several international conferences.  She has also supervised numerous Master's and PhD theses at MIT. 

In recent years, Dr. Seneff has focused her research interests back towards biology. She is concentrating mainly on the relationship between nutrition and health.  Since 2011, she has written 10 papers (7 as first author) in various medical and health-related journals on topics such as modern day diseases (e.g., Alzheimer, autism, cardiovascular diseases), analysis and search of databases of drug side effects using NLP techniques, and the impact of nutritional deficiencies and environmental toxins on human health.


S. Seneff. A Joint Synchrony/Mean-rate Model of Auditory Speech Processing. Journal of Phonetics, 16, 55-76, 1988.

S. Seneff, C. Wang and C. Burge. Gene Structure Prediction Using an Orthologous Gene of Known Exon-Intron Structure. Applied Bioinformatics  3(2-3) 81-90, 2004.

S. Seneff. Interactive Computer Aids for Acquiring Proficiency in Mandarin. Keynote Speech, 1-11, Proc. ISCSLP, Singapore, 2006.

S. Seneff, A. Lauritzen, R. Davidson, and L. Lentz-Marino. Is Endothelial Nitric Oxide Synthase a Moonlighting Protein Whose Day Job is Cholesterol Sulfate Synthesis? Implications for Cholesterol Transport, Diabetes and Cardiovascular Disease, Entropy 14, 2492-2530, 2012.

A. Samsel and S. Seneff. Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases. Entropy 15, 1416-1463, 2013.