CSAIL Event Calendar: Previous Series

Sequence- and structure-based approaches for annotating protein sequences

Speaker: Mona Singh , Princeton
Date: May 11 2011
Time: 11:30AM to 1:00PM
Location: TOC Lab 32-G575
Host: Bonnie Berger, MIT

For the typical proteome, there are no functional annotations for a third or more of its proteins. In this talk,I will discuss several sequence-and structure-based approaches we have been developing for annotating protein sequences in order to gain hints about their functions. I will describe computational approaches my group has
developed for predicting sites in protein sequences that interact with
small molecules and confer specificity; for identifying protein domains by exploiting sequence context; and for predicting interaction specificities for certain structural classes of transcription factors.

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