Cortically Constrained Volumetric Brain Image Registration using Harmonic Mapping
Speaker: Richard M. Leahy , University of Southern California
Date: November 29 2007
Time: 2:30PM to 3:30PM
Location: 32-D507
Host: Polina Golland, CSAIL
Contact: Polina Golland, x38005, polina@csail.mit.edu
Relevant URL: Intersubject registration of anatomical MR images is a necessary step
in group analysis of structural and functional neuroimaging
studies. Intensity-based volume registration methods can align
subcortical structures well, but the variability in sulcal folding
patterns typically results in misalignment of the cortical
surface. Conversely, surface-based registration using sulcal features
can produce excellent cortical alignment but the mapping between
brains is restricted to the cortical surface.
I will describe a method for volumetric registration that also
produces an accurate one-to-one point correspondence between cortical
surfaces. This is achieved by first parameterizing and aligning the
cortical surfaces using sulcal landmarks. We then use a combination of
harmonic mapping and minimization of elastic energy to align volumes
while retaining the surface correspondence. I will describe this
approach, present a comparative evaluation, and discuss applications
to the analysis of functional and structural data.
See other events that are part of Biomedical Imaging and Analysis 2007/2008
See other events happening in November 2007
