Multicellular genetic network modeling: directions and issues
Speaker: John Aach , Harvard
Date: February 9 2004
Time: 11:30AM to 12:50PM
Location: The Applied Mathematics Conference Room Building 2
Host: Peter Clote/ BC & Bonnie Berger/ MIT & CSAIL
Contact: Kathleen Dickey, 617 253 3037, kvdickey@mit.edu
Relevant URL: http://www-math.mit.edu/compbiosem/A key goal of recent systems biology is to generate mathematical models of
genetic networks capable of explaining the increasing amounts of molecular
data that are becoming available on cellular processes. Many models of
genetic networks have now been constructed, but most of them focus only on intracellular behavior; meanwhile, most biology involves mutually interacting cells whose behavior is governed by multicellular networks. This presentation reviews key directions and issues in multicellular genetic network modeling, including systems that have been extensively modeled, mathematical modeling techniques in use, options for representing cell populations, passive and active genetic networking, and the prospects of multicellular metabolic network modeling.
Refreshments: 11 am in The Applied Mathematics Common Room at MIT's Building 2, Room 349
The seminar is co-hosted by Professor Peter Clote of Boston College's Biology and Computer Science Departments and MIT Professor of Applied Math Bonnie Berger. Professor Berger is also affiliated with CSAIL & HST.
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