CSAIL Event Calendar: Previous Series
Analyzing and interrogating protein interaction maps using network schemas
Speaker: Mona Singh , Princeton
Relevant URL: http://www-math.mit.edu/compbiosem/
High-throughput technologies have led to proteome-scale interaction maps for several organisms. Computational analysis of these networks can reveal important principles of cellular organization and help uncover protein function. Towards such analysis, we introduce network schemas to specify recurring means with which biological processes are carried out. In this talk, I will discuss our approach to uncover and query network schemas within interaction networks, and show that network schemas can be used to uncover functionally cohesive subnetworks.